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NFL Week 5 game picks, schedule guide, fantasy football tips - ESPN Read more. However, Arizona's primary hope for winning this game lies with its run defense. What to know for fantasy: Derek Carr has completed over 70% of his passes in four straight games against the Chiefs and cleared 18 fantasy points in three of those contests. Matchup rating: 49.4 | Spread: LAC -6.5 (44.5), What to watch for: With Denver desperate for a win and fellow edge rusher Bradley Chubb done for the year because of an ACL injury, look for Von Miller to ignite the Broncos by getting after Philip Rivers, who has limited mobility. Stat to know: The Eagles are the only team to win the turnover battle in every game this season. Game of Midweek: Colts at Broncos (-3.5, 44 o/u) . Stat to know: The Titans rank 28th in the NFL in both sacks allowed (17) and pressure rate (34.0%). See Week 5 rankings. The Patriots have allowed a league-high five touchdowns to tight ends this season. Philadelphia is allowing a league-low 4.75 yards per pass, and the Cardinals are ranked 30th in passing yards per play (5.37). (1:17). Read more. NFL Week 5 Expert Picks - Straight Up - CBS Sports NFL Week 5 odds, point spreads, picks and best bets - The Washington Post The story of the Cowboys scout and prospect son Dallas just drafted, Legacy pick: Cardinals take great-great-nephew of team's first-ever draft pick, Buccaneers coach Todd Bowles explains handling of TE Cameron Brate's concussion, Veteran WR Cole Beasley retires after 11 NFL seasons, QB Kenny Pickett, Steelers begin work to get on 'same page', The Steelers' 2022 quarterback journey, and what happens next, LB Jamie Collins joins Patriots for fourth time, Swift likely out again vs. Patriots, source says, Bears designate WR N'Keal Harry for return; OL Cody Whitehair headed to IR, Inside Kelly Kleine's historic journey, from Vikings to Broncos, Justin Fields, Bears' struggling passing game looking for answers, Vikings riding ups and downs as Cousins learns new scheme, Dolphins' Mike McDaniel not fretting criticism over Tua Tagovailoa, Inside Jets' trade pursuit of Tyreek Hill, and how they rebounded, Dolphins say QB Tua Tagovailoa ruled out for Week 5 game vs. New York Jets, Browns' schedule gets difficult from now on, Garrett back at Browns practice for first time since car crash, Everything you need to know for the draft, The Seahawks have needed every bit of Geno Smith's unlikely success, Andy Dalton gave Saints' offense a spark, but bigger issues loom after 1-3 start, Saints' Alvin Kamara (rib) expects to play against Seahawks, Titans rookie WR Treylon Burks exits game with leg injury, Rivera OK with 'frustrations' amid 1-3 start, Commanders patient with Wentz despite rough stretch, RB Robinson returns to practice after being shot in robbery attempt, After loss, the Jaguars look to rebound against AFC South, How LSU and the SEC prepared Texans rookie Derek Stingley Jr. for the NFL, Former Jaguars QB Blake Bortles says he 'quietly' retired, Jimmie Ward year away from being among rarefied 49ers company, Mayfield struggles, but Panthers don't have another option, Nick Bosa says 49ers' defense has personnel to be 'best in the league', Mayfield takes blame for offense's struggles amid 1-3 start, Darnold's return from IR not close, coach Matt Rhule says, Miles Sanders' emergence makes the Eagles so much better, Defense keeps Cardinals afloat while offense figures it out, Jerry Jones: An 'injustice' not to give coach McCarthy credit.